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Go directly to the websites of top hotels in TX - from discount deals and affordable hotel rooms for the budget traveler to the best luxury four star and top five star accommodations.  You can also search for lodging that caters to your specific needs, such as extended stay hotels, family friendly, hotels for business traveler / event planning, suite / boutique hotels and much more.
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La Quinta Inn Houston Medical Center Astrodome
The La Quinta Inn Houston Reliant - Medical Center features all new rooms with free high-speed Internet access and more! The La Quinta Inn Houston Reliant - Medical Center is centrally located 1/2 mile west of Reliant Center, south of downtown Houston near the prestigious Texas Medical Center and MD Anderson (free shuttle weekdays). Visit the Museum district (Fine Arts, Natural Science, Holocaust, Texas Children's). We are close to restaurants and shopping at the Galleria and Rice Village. We are convenient to seasonal Livestock shows, rodeos, BBQ Cook-offs, and the annual Offshore Technology Conference. Start each day at the La Quinta Inn Houston Reliant - Medical Center Astrodome with a delicious Free Bright Side Breakfast prepared by our friendly staff off the lobby each morning. We have a refreshing swimming pool and a long list of amenities, including free high-speed Internet access and microfridges in all of our spacious rooms. Located on the southeast corner of the Buffalo Speedway at the Loop 610 intersection.
Hotel Address: 9911 Buffalo Speedway Houston TX 77054

La Quinta Inn Houston Greenway Plaza
The La Quinta Inn Houston Greenway Plaza is southwest of downtown with a clear shot to all local attractions: Texas Medical Center, Houston Zoo and Museum District, Rice University, Minute Maid Park-Toyota Center, Lakewood Church, and George R. Brown Convention Center. A short drive and you will reach Reliant Park, the Houston Rodeo and Livestock Show, as well as neighboring cities, West University Place TX, and Bellaire TX. We have plenty of great restaurants nearby to satisfy every taste, and world class shopping at the Houston Galleria. Our comfortable and spacious rooms - both interior and exterior corridor rooms available - are loaded with such amenities as free high-speed Internet access, an iron w/ironing board, hair dryer, and more. Select rooms even include a microwave and refrigerator. If you need space for your business, we have two meeting rooms available. We have a refreshing swimming pool and sprawling sundeck. Our friendly staff provides a Free Bright Side Breakfast every morning. Located east of 610 on US 59 at Weslyan. Free transportation to the Medical Center.
Hotel Address: 4015 Southwest Freeway Houston TX 77027-7499

Search our South Main accommodation section and book your last minute hotel reservations in South Main directly with each 2 star budget, 3 star mid priced, city center, boutique or first class, five star luxury hotel in the South Main area for the cheapest rates and best deals on South Main hoteles and hotel packages. Choose from some of the popular hotel brands & chains in the world, whether you want to find hotels in South Main on holiday, vacation or a family trip, or looking for a long stay hotel, aparthotel, a romantic weekend getaway, or a honeymoon hotel in South Main. Some common ways to find this page include hotelsin South Main, South MainTexas, otels, hotelroom, hotles, reservation, cheep, South Mainhotels, hotesl, hotelSouth Main, otel, hotels inSouth Main, hotle, aera, reservatiom, hotelesen, deasl, roms, hoyel, donwtown, hotelrooms, hoetl, South Mainhotel and hoytel, rseervation, hotelsSouth Main downtonw, hoteles en South Main, en, chaep, hotelin South Main, hottel, Ho8ston, Houstin, Hiuston, Houst9n, Hohston, Houstob, Houstln, Houstkn, Hoiston, , resrevation, hotell, hotelsSouth Main

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